The following South Carolina prep players have advanced to professional soccer:
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- Craig (Forest) Appleby, Irmo HS '89 (Wofford/Charlotte) -- Current Head Coach of Johns Hopkins University (MD, 2008-14), Former Head Coach at Emory & Henry (VA, 2002-07); Former Assistant Coach at Wofford College and Washington & Lee University; Tus Celle (Germany 3rd Division, 1994); Raleigh Flyers (USISL, 1995); Charleston Battery (USISL, 1996); Richmond Kickers (A-League, 1997)
- Herbert Cojulun, Brookland-Cayce HS '13 -- Club Xelaju (Guatemala)
- Shawn Ferguson, Northwestern HS (Charleston) -- Charleston Battery
- Hunter Gilstrap, Lexington HS '01 (Clemson / Charleston) -- Miami FC, Cleveland City Stars, Performance FC Phoenix, Maritzburg United, Pittsburgh Riverhounds; Coached at the University of Pittsburgh
- Ben Hollingsworth, Bishop England HS (Charleston) -- Charleston Battery, Maccabi Tel Aviv FC
- Willie Hunt, Eastside HS '06 (Francis Marion) -- tba
- Wes Knight, Wren HS (Charleston) -- tba
- Ryan Kurtz, Irmo HS '93 (Charleston) -- tba
- Troy Lesesne, Brookland-Cayce HS '01 (Charleston) -- Current Head Coach of New Mexico United; Charlotte Independence Assistant Coach; Vancouver Whitecaps/Charleston Battery Assistant Coach; College of Charleston Assistant Coach; Charleston Battery Player
- Alex Martinez, Northwestern HS '10 (High Point/N.C. State) -- tba
- Enzo Martinez, Northwestern HS '09 (North Carolina) -- tba
- Zach Prince, Irmo HS (Charleston) '06 -- tba
- Austin Savage, Stratford HS (Clemson) -- tba
- Temoc Suarez, Bishop England HS (North Carolina) -- tba
- Sebastian Velasquez, Greenville HS (Spartanburg Methodist) -- Real Salt Lake, NYCFC
- John Wilson, Seneca HS (Clemson) -- DC United, Charleston Battery
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